Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723788 | 0.88 | BACE1 (0.59) | BACE1NPC1POLBKDM4ERAB9A | |
| SCHEMBL30701889 | 0.88 | BACE1 (0.59) | BACE1NPC1POLBKDM4ERAB9A | |
| SCHEMBL30701890 | 0.88 | BACE1 (0.59) | BACE1NPC1POLBKDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL9723743 | 0.86 | BACE1 (0.58) | BACE1NPC1POLBKDM4ERAB9A | |
| SCHEMBL7083789 | 0.84 | SMN1; SMN2 (0.64) | BACE1NPC1POLBKDM4ERAB9A | |
| SCHEMBL8142093 | 0.84 | KDM4E (0.61) | BACE1NPC1POLBKDM4ERAB9A | |
| SCHEMBL10513975 | 0.82 | BACE1 (0.54) | BACE1NPC1POLBKDM4ERAB9A | |
| SCHEMBL3824865 | 0.81 | BACE1 (0.63) | BACE1NPC1POLBKDM4ERAB9A | |
| SCHEMBL31273249 | 0.80 | BACE1 (0.61) | BACE1NPC1POLBKDM4ERAB9A | |
| SCHEMBL14034583 | 0.79 | KDM4E (0.56) | POLBKDM4EMEN1GLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114613-A | High-speed responsive, stable films; controlling the mesomorphic state and temperature | CANON KABUSHIKI KAISHA (JP) | 1992-05-19 | — | — | US | disclosed |
| US-4882085-A | Lactic acid derivative and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1989-11-21 | — | — | US | disclosed |