Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330589 | 0.85 | KDM4E (0.57) | KDM4EMAPTMAPK1LMNACYP3A4 | |
| SCHEMBL7326050 | 0.85 | KDM4E (0.53) | KDM4EMAPTMAPK1LMNACYP3A4 | |
| SCHEMBL14744132 | 0.85 | KDM4E (0.72) | KDM4EMAPTMAPK1LMNACYP3A4 | |
| SCHEMBL11703452 | 0.84 | ALDH1A1 (0.40) | KDM4EMAPTMAPK1CYP3A4POLB | |
| SCHEMBL312364 | 0.84 | KDM4E (0.51) | KDM4EMAPTMAPK1LMNACYP3A4 | |
| SCHEMBL27580216 | 0.82 | KDM4E (0.58) | KDM4EMAPTMAPK1LMNACYP3A4 | |
| SCHEMBL11197823 | 0.80 | NPC1 (0.55) | KDM4EMAPTMAPK1LMNACYP3A4 | |
| SCHEMBL23668248 | 0.80 | KDM4E (0.47) | KDM4EMAPTMAPK1LMNACYP3A4 | |
| SCHEMBL9723737 | 0.79 | BACE1 (0.56) | KDM4EMAPTMAPK1LMNAPOLB | |
| SCHEMBL4360840 | 0.78 | KDM4E (0.73) | KDM4EMAPTMAPK1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275017-A1 | AROMATIC SULFENATES FOR TYPE I PHOTOTHERAPY | MALLINCKRODT LLC | 2008-11-06 | — | — | US | disclosed |
| US-7235685-B2 | Aromatic sulfenates for type I phototherapy | MALLINCKRODT, INC. (US) | 2007-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275017-A1 | AROMATIC SULFENATES FOR TYPE I PHOTOTHERAPY | TYR, SULT1A1, TPST2 | KDM4E 2085/4885MAPT 1463/4885MAPK1 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.