Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723936 | 0.90 | ALDH1A1 (0.38) | PPARGMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9723941 | 0.80 | KMT2A (0.41) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL9265847 | 0.77 | MEN1 (0.47) | PPARGMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9271308 | 0.69 | MAPT (0.61) | PPARGMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9269846 | 0.68 | MEN1 (0.42) | KMT2AMEN1 | |
| SCHEMBL9272311 | 0.66 | KMT2A (0.42) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL9263567 | 0.66 | TP53 (0.45) | MAPTKMT2AMEN1SLC6A2SLC6A3 | |
| SCHEMBL5085480 | 0.66 | PPARG (0.71) | PPARGMAPTRAB9AKMT2AMAPK1 | |
| SCHEMBL9261290 | 0.65 | KMT2A (0.46) | PPARGMAPTRAB9AKMT2ANPC1 | |
| SCHEMBL19248489 | 0.65 | KMT2A (0.56) | PPARGMAPTRAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089504-A | SUBSTITUTED 4-AMINOQUINOLINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-02-18 | — | — | US | disclosed |