Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723924 | 0.80 | PPARG (0.44) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL9263567 | 0.78 | TP53 (0.45) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL9272311 | 0.76 | KMT2A (0.42) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL9723937 | 0.71 | CSF1R (0.45) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL9271491 | 0.71 | GABRA1 (0.69) | KMT2AALDH1A1L3MBTL1HPGDMEN1 | |
| SCHEMBL9723936 | 0.71 | ALDH1A1 (0.38) | KMT2AALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL9271570 | 0.69 | GABRA1 (0.57) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23134300 | 0.69 | KMT2A (0.79) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL2938811 | 0.68 | KMT2A (0.57) | KMT2ATDP1SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL9265847 | 0.67 | MEN1 (0.47) | KMT2AMAPTMAPK1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089504-A | SUBSTITUTED 4-AMINOQUINOLINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-02-18 | — | — | US | disclosed |