Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.49 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | CBX7 | O95931 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30818027 | 0.90 | APEX1 (0.66) | APEX1TIMP3MEN1USP2RECQL | |
| SCHEMBL4649703 | 0.90 | APEX1 (0.66) | APEX1TIMP3MEN1USP2RECQL | |
| SCHEMBL375680 | 0.85 | TIMP3 (0.75) | APEX1TIMP3MEN1USP2RECQL | |
| SCHEMBL7653343 | 0.84 | APEX1 (0.71) | APEX1TIMP3MEN1USP2RECQL | |
| SCHEMBL7894746 | 0.82 | APEX1 (0.59) | APEX1TIMP3MEN1USP2RECQL | |
| SCHEMBL9723988 | 0.82 | CASP6 (0.48) | APEX1TIMP3MEN1USP2RECQL | |
| SCHEMBL10949633 | 0.82 | APEX1 (0.55) | APEX1TIMP3MEN1USP2RECQL | |
| SCHEMBL1413171 | 0.81 | AURKB (0.52) | APEX1TIMP3MEN1USP2RECQL | |
| SCHEMBL9350837 | 0.80 | TIMP3 (0.49) | APEX1TIMP3MEN1USP2RECQL | |
| SCHEMBL9411865 | 0.80 | APEX1 (1.00) | APEX1MEN1KMT2AHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082963-A | Water solubility | HOECHST CELANESE CORPORATION (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0210331-B1 | WATER SOLUBLE MONO AND DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-15 | — | — | EP | disclosed |
| US-4703111-A | Water-soluble compounds containing one or two (nitrophenylamino)-phenylamino-chlorotriazinylamino groups, the nitrophenylamino being additionally substituted by a fiber-reactive group of the vinylsulfonyl series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT A CORP. OF GERMANY (DE) | 1987-10-27 | — | — | US | disclosed |
| EP-0210331-A1 | Water soluble mono and disazo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-02-04 | — | — | EP | disclosed |