Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942276 | 0.89 | CASP6 (0.51) | CASP6TIMP3MEN1USP2RECQL | |
| SCHEMBL10796039 | 0.87 | TIMP3 (0.42) | CASP6TIMP3MEN1USP2RECQL | |
| SCHEMBL10506764 | 0.86 | TIMP3 (0.43) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL9723952 | 0.82 | APEX1 (0.66) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL1804480 | 0.81 | TIMP3 (0.51) | CASP6TIMP3MEN1USP2RECQL | |
| SCHEMBL9765207 | 0.81 | AURKB (0.52) | CASP6TIMP3MEN1USP2RECQL | |
| SCHEMBL10948594 | 0.80 | NT5E (0.44) | CASP6TIMP3MEN1USP2RECQL | |
| SCHEMBL7653343 | 0.80 | APEX1 (0.71) | CASP6TIMP3MEN1USP2RECQL | |
| SCHEMBL7893088 | 0.79 | CASP6 (0.43) | CASP6TIMP3MEN1USP2RECQL | |
| SCHEMBL7894762 | 0.78 | AURKB (0.56) | CASP6TIMP3MEN1USP2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082963-A | Water solubility | HOECHST CELANESE CORPORATION (US) | 1992-01-21 | — | — | US | disclosed |
| US-4703111-A | Water-soluble compounds containing one or two (nitrophenylamino)-phenylamino-chlorotriazinylamino groups, the nitrophenylamino being additionally substituted by a fiber-reactive group of the vinylsulfonyl series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT A CORP. OF GERMANY (DE) | 1987-10-27 | — | — | US | disclosed |
| EP-0210331-A1 | Water soluble mono and disazo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-02-04 | — | — | EP | disclosed |