Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | PPIG | Q13427 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5343038 | 0.85 | BLM (0.56) | BLMALDH1A1LMNAKMT2AHTT | |
| SCHEMBL687447 | 0.85 | SMN1; SMN2 (0.52) | FDPSSMN1; SMN2HIF1AALDH1A1LMNA | |
| SCHEMBL7908766 | 0.85 | SMN1; SMN2 (0.52) | FDPSSMN1; SMN2HIF1AALDH1A1LMNA | |
| SCHEMBL7908936 | 0.85 | SMN1; SMN2 (0.52) | FDPSSMN1; SMN2HIF1AALDH1A1LMNA | |
| SCHEMBL8740577 | 0.84 | KDM4E (0.45) | BLMALDH1A1LMNAKMT2AHTT | |
| SCHEMBL2241052 | 0.81 | LDHA (0.49) | SMN1; SMN2ALDH1A1LMNAHTTKDM4E | |
| SCHEMBL9658100 | 0.79 | BLM (0.44) | FDPSBLMSMN1; SMN2HIF1APPIB | |
| SCHEMBL5160750 | 0.78 | CYP2C19 (0.48) | ALDH1A1CYP1A2TDP1TSHRPOLB | |
| SCHEMBL5160741 | 0.78 | CYP2C19 (0.48) | ALDH1A1CYP1A2TDP1TSHRPOLB | |
| SCHEMBL2164197 | 0.76 | PTPRC (0.37) | BLMSMN1; SMN2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095006-A | Enzyme inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |