Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPIB | P23284 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | PPIG | Q13427 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246789 | 0.85 | CYP3A4 (0.43) | BLMCYP3A4ALDH1A1TDP1FDPS | |
| SCHEMBL11529107 | 0.84 | SMN1; SMN2 (0.53) | CYP3A4ALDH1A1FDPSSMN1; SMN2HIF1A | |
| SCHEMBL17621316 | 0.80 | LDHA (0.50) | SMN1; SMN2PPARAPOLBKMT2A | |
| SCHEMBL10710068 | 0.80 | SMN1; SMN2 (0.53) | CYP3A4ALDH1A1FDPSSMN1; SMN2HIF1A | |
| SCHEMBL9724009 | 0.79 | FDPS (0.46) | BLMCYP3A4ALDH1A1TDP1FDPS | |
| SCHEMBL1931036 | 0.79 | PPARA (0.43) | BLMCYP3A4ALDH1A1TDP1FDPS | |
| Ammonia Solution, Strong SCHEMBL25250245 | 0.78 | SMN1; SMN2 (0.52) | CYP3A4ALDH1A1FDPSSMN1; SMN2HIF1A | |
| SCHEMBL11604406 | 0.77 | ITGB1 (0.37) | FDPSPPIBPPIAPPIDPPIG | |
| SCHEMBL6668736 | 0.76 | BLM (0.52) | BLMCYP3A4ALDH1A1TDP1FDPS | |
| SCHEMBL8530006 | 0.75 | PPIB (0.40) | CYP3A4ALDH1A1FDPSHIF1APPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172147-B1 | AMIDE DERIVATIVES OF 2-(P-AMINOBENZYL)-BUTYRIC ACID AND ESTERS THEREOF HAVING HYPOLIPIDEMIZING ACTIVITY | Medosan Industrie Biochimiche Riunite S.r.l. (IT) | 1992-06-03 | — | — | EP | disclosed |
| EP-0172147-A2 | Amide derivatives of 2-(p-aminobenzyl)-butyric acid and esters thereof having hypolipidemizing activity | Medosan Industrie Biochimiche Riunite S.r.l. (IT) | 1986-02-19 | — | — | EP | disclosed |