Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | PTGIR | P43119 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724109 | 0.83 | THRB (0.39) | MEN1KMT2AALDH1A1BLMPOLB | |
| SCHEMBL19259920 | 0.82 | POLB (0.37) | MEN1KMT2ANPSR1ALDH1A1LMNA | |
| SCHEMBL9724100 | 0.82 | KDM4E (0.48) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL9538802 | 0.81 | RHEB (0.39) | MEN1KMT2APTGIRNPSR1ALDH1A1 | |
| SCHEMBL9724095 | 0.80 | TP53 (0.40) | MEN1KMT2APTGIRALDH1A1POLB | |
| SCHEMBL13067234 | 0.78 | DHFR (0.36) | MEN1KMT2APTGIRNPSR1MAOA | |
| SCHEMBL9724126 | 0.75 | KDM4E (0.47) | NPSR1ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL19274531 | 0.75 | GAA (0.44) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13026621 | 0.74 | HPGD (0.37) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28649609 | 0.73 | ICAM1 (0.39) | MEN1KMT2APTGIRNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |