Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MMP12 | P39900 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724093 | 0.80 | MEN1 (0.33) | POLBKMT2AMEN1PTGIRMAPT | |
| SCHEMBL9724109 | 0.80 | THRB (0.39) | TP53POLBMMP2KMT2AMEN1 | |
| SCHEMBL9724097 | 0.73 | ALOX5 (0.41) | MMP2MMP9MMP12PTGIR | |
| SCHEMBL11521743 | 0.72 | LTA4H (0.51) | POLBKMT2AMEN1PTGIRKDM4E | |
| SCHEMBL11398559 | 0.70 | PKM (0.53) | TP53POLBMMP2MMP9MMP12 | |
| SCHEMBL7593054 | 0.68 | ALDH1A1 (0.43) | PTGIRMAPTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL482369 | 0.67 | CA1 (0.65) | POLBKMT2AMEN1PTGIRGAA | |
| SCHEMBL157282 | 0.66 | ALDH1A1 (0.62) | KMT2AMEN1GAAMAPTHTT | |
| SCHEMBL9724126 | 0.66 | KDM4E (0.47) | POLBGAAKDM4EMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11848856 | 0.65 | CA1 (0.61) | POLBKMT2AMEN1PTGIRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |