SCHEMBL9724236

SCHEMBL9724236

Cc1ccc(N(c2ccc(C)cc2)c2ccccc2C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP2C19 P33261 2/20 0.41
ACHE P22303 3/20 0.39
C5AR1 P21730 1/20 0.38
LMNA P02545 3/20 0.38
ALOX12 P18054 1/20 0.38
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 3/20 0.36
HCRTR2 O43614 1/20 0.36
CYP1A2 P05177 2/20 0.34
CYP2A6 P11509 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
APP P05067 1/20 0.34
MAPT P10636 2/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10053558 0.96 CYP2C19 (0.42) TSHRALDH1A1CYP2C19ACHEC5AR1
SCHEMBL13480247 0.95 TSHR (0.42) TSHRALDH1A1CYP2C19ACHEC5AR1
SCHEMBL13152210 0.94 HSD17B1 (0.41) TSHRALDH1A1CYP2C19ACHEC5AR1
SCHEMBL9161894 0.94 ALDH1A1 (0.43) TSHRALDH1A1CYP2C19ACHEC5AR1
SCHEMBL4893894 0.91 ACHE (0.43) TSHRALDH1A1CYP2C19ACHELMNA
SCHEMBL10053544 0.90 HSD17B1 (0.39) TSHRALDH1A1CYP2C19ACHEC5AR1
SCHEMBL14047707 0.90 HSD17B1 (0.39) TSHRALDH1A1CYP2C19ACHEC5AR1
SCHEMBL25446015 0.89 MAPT (0.40) TSHRALDH1A1CYP2C19ACHEC5AR1
SCHEMBL4473067 0.89 ALDH1A1 (0.39) TSHRALDH1A1CYP2C19ACHELMNA
SCHEMBL9193172 0.89 ALDH1A1 (0.39) TSHRALDH1A1CYP2C19ACHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10558132-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2020-02-11 US disclosed
US-20090214968-A1 MIXTURE OF BISAMINE COMPOUNDS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR FORMING IMAGE, AND IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-08-27 US disclosed
US-20090214968-A1 MIXTURE OF BISAMINE COMPOUNDS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR FORMING IMAGE, AND IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-08-27 US disclosed
US-7241543-B2 Image forming method, a photoreceptor used for the apparatus, and an image forming unit KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-10 US disclosed
US-7241543-B2 Image forming method, a photoreceptor used for the apparatus, and an image forming unit KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-10 US disclosed
US-7238457-B2 Electrophotographic photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-03 US disclosed
US-7238457-B2 Electrophotographic photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-03 US disclosed
US-7175954-B2 Electrophotographic photoreceptor KONICA MINOLTA HOLDINGS, INC. (JP) 2007-02-13 US disclosed
US-7175954-B2 Electrophotographic photoreceptor KONICA MINOLTA HOLDINGS, INC. (JP) 2007-02-13 US disclosed
US-5169987-A Light sensitive charge generating compounds for electrography FUJI XEROX CO., LTD. (JP) 1992-12-08 US disclosed
US-5047589-A Electrophotographic light-sensitive material containing squarylium compound FUJI XEROX CO. LTD. (JP) 1991-09-10 US disclosed
US-5024911-A High sensitivity FUJI XEROX CO., LTD. (JP) 1991-06-18 US disclosed
US-5023356-A Novel tetracyanoanthraquinodimethane derivatives and process for producing same FUJI XEROX CO., LTD. (JP) 1991-06-11 US disclosed
US-4990634-A Novel tetracyanoanthraquinodimethane derivatives and process for producing same FUJI XEROX CO., LTD. (JP) 1991-02-05 US disclosed
US-4822704-A IMPROVED SENSITIVITY AND DURABILITY FUJI XEROX CO., LTD. (JP) 1989-04-18 US disclosed
US-4820600-A Electrophotographic photoreceptor having a bisazo compound FUJI XEROX CO., LTD. (JP) 1989-04-11 US disclosed