Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.76 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.76 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.76 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL9724261 | 0.90 | CXCL8 (0.62) | PTGS2CXCL8AKR1B1PTGS1GLO1 | |
| SCHEMBL2238865 | 0.87 | PTGS2 (0.57) | PTGS2CXCL8AKR1B1PTGS1GLO1 | |
| SCHEMBL11807843 | 0.86 | CXCL8 (0.60) | PTGS2CXCL8AKR1B1PTGS1GLO1 | |
| Tolmetin SCHEMBL11325188 | 0.86 | PTGS2 (1.00) | PTGS2CXCL8AKR1B1PTGS1GLO1 | |
| Tolmetin SCHEMBL3150 | 0.86 | PTGS2 (1.00) | PTGS2CXCL8AKR1B1PTGS1GLO1 | |
| SCHEMBL12608965 | 0.86 | PTGS2 (0.78) | PTGS2CXCL8AKR1B1PTGS1GLO1 | |
| Tolmetin SCHEMBL29461 | 0.85 | PTGS2 (0.97) | PTGS2CXCL8AKR1B1PTGS1GLO1 | |
| Tolmetin SCHEMBL11486460 | 0.85 | PTGS2 (0.97) | PTGS2CXCL8AKR1B1PTGS1GLO1 | |
| Tolmetin SCHEMBL28562007 | 0.85 | PTGS2 (0.97) | PTGS2CXCL8AKR1B1PTGS1GLO1 | |
| Tolmetin SCHEMBL5980424 | 0.85 | PTGS2 (0.97) | PTGS2CXCL8AKR1B1PTGS1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4210963-A | — | — | None | — | — | JP | disclosed |
| EP-4272761-A2 | COMPOSITIONS FOR TREATING OPHTHALMIC CONDITIONS | Medicon Pharmaceuticals, Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| JP-H04210963-A | PYRROLACETIC AMIDE | SIGMA TAU IND FARMACEUT RIUNITE SPA | 1992-08-03 | — | — | JP | disclosed |
| US-4882349-A | ANALGESICS, ANTIPYRETICS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A (IT) | 1989-11-21 | — | — | US | disclosed |
| US-4578481-A | ANALGESICS; ANTIPYRETIC, ANTITUSSIVE, AND ANTISECRETORY AGENTS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1986-03-25 | — | — | US | disclosed |
| US-3998844-A | WITH AN AROYL CHLORIDE TO FORM A 5-AROYL-1-ALKYLPYRROLE-2-ACETIC ACID DERIVATIVE | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-12-27 | — | — | US | disclosed |