Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724249 | 0.90 | PTGS2 (0.76) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL11877048 | 0.83 | CXCL8 (0.70) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL12608965 | 0.80 | PTGS2 (0.78) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL2238865 | 0.78 | PTGS2 (0.57) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| Tolmetin SCHEMBL28723181 | 0.78 | PTGS2 (0.94) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL13653108 | 0.78 | PTGS2 (0.74) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| Tolmetin SCHEMBL3150 | 0.77 | PTGS2 (1.00) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| Tolmetin SCHEMBL11325188 | 0.77 | PTGS2 (1.00) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL11807843 | 0.77 | CXCL8 (0.60) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL13241359 | 0.77 | CXCL8 (0.72) | CXCL8AKR1B1PTGS1PTGS2GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4210963-A | — | — | None | — | — | JP | disclosed |
| JP-H04210963-A | PYRROLACETIC AMIDE | SIGMA TAU IND FARMACEUT RIUNITE SPA | 1992-08-03 | — | — | JP | disclosed |