Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724330 | 0.80 | RXRA (0.52) | RXRARARARARBRARGRXRB | |
| SCHEMBL9587601 | 0.71 | CYP26A1 (0.38) | RXRARARARARBRARGCYP1A2 | |
| SCHEMBL28286504 | 0.70 | BLM (0.47) | CYP2C19PTGS1POLBCYP1A2GAA | |
| SCHEMBL15546561 | 0.70 | KMT2A (0.54) | CYP2C19POLBCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL1147878 | 0.70 | POLB (0.50) | CYP2C19PTGS1POLBALDH1A1GAA | |
| SCHEMBL10355937 | 0.69 | RXRA (0.64) | RXRARARARARBRARGRXRB | |
| SCHEMBL3333892 | 0.69 | AKR1C3 (0.45) | CYP2C19AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL11250019 | 0.69 | LMNA (0.40) | RXRACYP1A2ALDH1A1CYP26A1CYP3A4 | |
| SCHEMBL7782012 | 0.69 | ABCB11 (0.41) | RXRARXRBALDH1A1GAA | |
| SCHEMBL8824861 | 0.69 | ABCB11 (0.41) | RXRARXRBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286523-B1 | AROMATIC DERIVATIVES OF BUTYRIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR COSMETIC AND PHARMACEUTICAL USE | L'OREAL (FR) | 1992-01-22 | — | — | EP | claimed |