Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbromal SCHEMBL9724461 | 0.99 | ALDH1A1 (0.47) | ALDH1A1ESR1CYP19A1ESR2POLB | |
| Carbromal SCHEMBL23051624 | 0.87 | LMNA (0.37) | ALDH1A1POLBKMT2AMEN1MAPT | |
| Carbromal SCHEMBL9170995 | 0.80 | CYP2C19 (0.42) | ALDH1A1POLBKMT2AMEN1MAPT | |
| Carbromal SCHEMBL4351621 | 0.77 | CRBN (0.39) | MAPT | |
| Carbromal SCHEMBL15057476 | 0.77 | CRBN (0.39) | MAPT | |
| 4-Nitroaniline SCHEMBL7505578 | 0.77 | ALDH1A1 (0.82) | ALDH1A1ESR1CYP19A1ESR2POLB | |
| 4-Nitroaniline SCHEMBL28323077 | 0.76 | ALDH1A1 (0.67) | ALDH1A1ESR1CYP19A1ESR2KMT2A | |
| Carbromal SCHEMBL23051626 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4ESMN1; SMN2NOS1 | |
| Carbromal SCHEMBL6249616 | 0.75 | CRBN (0.37) | MAPT | |
| Carbromal SCHEMBL4352660 | 0.75 | CRBN (0.37) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162489-A | Containing a 1,1,3-trimethylphenylindane moiety | AKZO N.V. (NL) | 1992-11-10 | — | — | US | disclosed |
| US-4980504-A | WHICH HAVE HIGH GLASS TRANSITION TEMPERATURES | AKZO N.V. (NL) | 1990-12-25 | — | — | US | disclosed |