Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SELL | P14151 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548003 | 0.87 | GAA (0.47) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL9724381 | 0.86 | GAA (0.46) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL153055 | 0.81 | GAA (0.74) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL30049382 | 0.81 | GAA (0.74) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL21076208 | 0.80 | GAA (0.72) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2530820 | 0.80 | GAA (0.72) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL27952523 | 0.80 | GAA (0.72) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL21328344 | 0.78 | GAA (0.70) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL21328360 | 0.78 | GAA (0.70) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL347877 | 0.78 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158948-A | Treating neurological and psychological disorders | ABBOTT LABORATORIES (US) | 1992-10-27 | — | — | US | disclosed |