Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548003 | 0.86 | GAA (0.47) | GAASMN1; SMN2STAT3ALDH1A1TDP1 | |
| SCHEMBL9724440 | 0.86 | GAA (0.64) | GAASMN1; SMN2STAT3ALDH1A1TDP1 | |
| SCHEMBL76377 | 0.82 | LMNA (0.59) | GAASMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL3616256 | 0.79 | ALDH1A1 (0.53) | GAASMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL3659918 | 0.79 | GAA (0.50) | GAASMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL3225685 | 0.78 | HTT (0.55) | GAASMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL1462899 | 0.78 | HDAC1 (0.57) | GAASMN1; SMN2ALDH1A1TDP1LMNA | |
| SCHEMBL2405481 | 0.76 | CCR5 (0.52) | GAAALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL2391312 | 0.76 | TSHR (0.73) | GAAALDH1A1TDP1TSHRNFKB1 | |
| SCHEMBL9808605 | 0.75 | PTGS1 (0.62) | GAASMN1; SMN2ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158948-A | Treating neurological and psychological disorders | ABBOTT LABORATORIES (US) | 1992-10-27 | — | — | US | disclosed |