Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.44 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.44 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.44 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11702512 | 0.99 | ALOX15 (0.51) | THRATHRBALOX15TOP2APOLM | |
| SCHEMBL9440210 | 0.89 | THRA (0.53) | THRATHRBALOX15TOP2AKMT2A | |
| Hydrochloric Acid SCHEMBL9724775 | 0.88 | THRA (0.52) | THRATHRBALOX15TOP2AKMT2A | |
| SCHEMBL27765388 | 0.83 | MAPT (0.57) | ALOX15TOP2AMAPTKMT2ANPC1 | |
| SCHEMBL9626722 | 0.82 | THRA (0.67) | THRATHRBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9307742 | 0.82 | THRA (0.67) | THRATHRBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9578543 | 0.82 | THRA (0.67) | THRATHRBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11321553 | 0.82 | THRA (0.67) | THRATHRBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9626799 | 0.82 | THRA (0.67) | THRATHRBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11315387 | 0.82 | THRA (0.67) | THRATHRBALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100579-A | POLYPHENYL-BASED ESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 1992-03-31 | — | — | US | disclosed |
| EP-0191600-B1 | POLYPHENYL-BASED ESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4911861-A | Mixture of at least two components | AJINOMOTO CO., INC. (JP) | 1990-03-27 | — | — | US | disclosed |
| US-4728458-A | FERROELECTRIC | AJINOMOTO CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0191600-A2 | Polyphenyl-based ester compounds and liquid crystal compositions containing same | AJINOMOTO CO., INC. (JP) | 1986-08-20 | — | — | EP | disclosed |