Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | FPR2 | P25090 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28119598 | 0.89 | KMT2A (0.65) | KMT2APOLBL3MBTL1FPR2ALDH1A1 | |
| SCHEMBL9724805 | 0.86 | RAB9A (0.65) | KMT2AALDH1A1RAB9A | |
| SCHEMBL7271417 | 0.86 | MME (0.65) | KMT2AACEALDH1A1MAPTMME | |
| SCHEMBL9724975 | 0.85 | HPGD (0.54) | KMT2AACEALDH1A1MAPTMME | |
| SCHEMBL9724984 | 0.84 | LMNA (0.61) | POLBACEFPR2ALDH1A1MAPT | |
| SCHEMBL9724811 | 0.83 | MME (0.65) | KMT2AACEALDH1A1MAPTMME | |
| SCHEMBL7373900 | 0.83 | CYP1A2 (0.56) | KMT2AACEALDH1A1MAPTRAB9A | |
| SCHEMBL390864 | 0.82 | MME (0.57) | KMT2AACEALDH1A1MAPTMME | |
| SCHEMBL9724827 | 0.82 | MEN1 (0.59) | KMT2AACEALDH1A1MAPTMME | |
| SCHEMBL9724992 | 0.82 | MME (0.57) | KMT2AACEALDH1A1MAPTMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | claimed |
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |