Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MME | P08473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724783 | 0.85 | KMT2A (0.62) | MMEALDH1A1ACEMAPTKMT2A | |
| SCHEMBL7271417 | 0.84 | MME (0.65) | HPGDMMEALDH1A1ACEMAPK1 | |
| SCHEMBL9724801 | 0.82 | HPGD (0.56) | HPGDALDH1A1MEN1KMT2AKLK7 | |
| Benzene SCHEMBL7278973 | 0.82 | KLK7 (0.53) | HPGDALDH1A1MAPTKMT2AKLK7 | |
| SCHEMBL9724811 | 0.81 | MME (0.65) | HPGDMMEALDH1A1ACEMAPK1 | |
| SCHEMBL7373900 | 0.81 | CYP1A2 (0.56) | HPGDMMEALDH1A1ACEMAPK1 | |
| SCHEMBL390864 | 0.80 | MME (0.57) | HPGDMMEALDH1A1ACEMAPK1 | |
| SCHEMBL9724827 | 0.80 | MEN1 (0.59) | HPGDMMEALDH1A1ACEMAPK1 | |
| SCHEMBL9724992 | 0.80 | MME (0.57) | HPGDMMEALDH1A1ACEMAPK1 | |
| SCHEMBL9724810 | 0.80 | MME (0.54) | HPGDMMEALDH1A1ACEMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |