Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566813 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHRAKR1C1NQO2MAPK1 | |
| SCHEMBL566814 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHRAKR1C1NQO2MAPK1 | |
| Hydrochloric Acid SCHEMBL11771744 | 0.98 | ALDH1A1 (0.52) | ALDH1A1TSHRAKR1C1NQO2MAPK1 | |
| SCHEMBL566757 | 0.88 | ALDH1A1 (0.51) | ALDH1A1TSHRNQO2MAPK1TDP1 | |
| SCHEMBL566758 | 0.88 | ALDH1A1 (0.51) | ALDH1A1TSHRNQO2MAPK1TDP1 | |
| SCHEMBL28593357 | 0.88 | MAPT (0.56) | ALDH1A1TSHRNQO2MAPTMEN1 | |
| SCHEMBL5725732 | 0.86 | MEN1 (0.49) | ALDH1A1TSHRAKR1C1NQO2MAPT | |
| SCHEMBL22500964 | 0.86 | MAOB (0.50) | ALDH1A1TSHRAKR1C1NQO2MAPK1 | |
| SCHEMBL20400451 | 0.86 | MAOB (0.50) | ALDH1A1TSHRAKR1C1NQO2MAPK1 | |
| SCHEMBL3725584 | 0.86 | CYP1B1 (0.50) | ALDH1A1TSHRAKR1C1NQO2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708310-B2 | Phenanthroindolizidine and phenanthroquinolizidine alkaloid having a hydroxyl group on the phenanthrene ring thereof, preparation method and use thereof | CHINA MEDICAL UNIVERSITY (TW) | 2017-07-18 | — | — | US | claimed |
| US-20170152257-A1 | PHENANTHROINDOLIZIDINE AND PHENANTHROQUINOLIZIDINE ALKALOID HAVING A HYDROXYL GROUP ON THE PHENANTHRENE RING THEREOF, PREPARATION METHOD AND USE THEREOF | CHINA MEDICAL UNIVERSITY (TW) | 2017-06-01 | — | — | US | claimed |
| CN-120682125-B | 1-Hydroxy-1-sodium sulfonate structural compound based on cinnamaldehyde derivative, and preparation method and application thereof | 中国农业大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-117945820-A | Method for synthesizing alpha, beta-unsaturated aldehyde compound by copper catalysis | 江苏海洋大学 | 2024-04-30 | — | — | CN | disclosed |
| US-9708310-B2 | Phenanthroindolizidine and phenanthroquinolizidine alkaloid having a hydroxyl group on the phenanthrene ring thereof, preparation method and use thereof | CHINA MEDICAL UNIVERSITY (TW) | 2017-07-18 | — | — | US | disclosed |
| US-20170152257-A1 | PHENANTHROINDOLIZIDINE AND PHENANTHROQUINOLIZIDINE ALKALOID HAVING A HYDROXYL GROUP ON THE PHENANTHRENE RING THEREOF, PREPARATION METHOD AND USE THEREOF | CHINA MEDICAL UNIVERSITY (TW) | 2017-06-01 | — | — | US | disclosed |
| US-20110295019-A1 | Method for Producing Hydroxymethyl Diphenyloxiranes and Corresponding 1-azolylmethyl-1,2-diphenyloxiranes | BASF SE (DE) | 2011-12-01 | — | — | US | disclosed |
| EP-0975224-A1 | PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS | MONSANTO COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| US-6020287-A | USING MIXTURE OF HERBICIDE AND PHENYL-SUBSTITUTED OLEFIN COMPOUND | MONSANTO COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| WO-1998033385-A1 | PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS | MONSANTO COMPANY (US) | 1998-08-06 | — | — | WO | disclosed |
| US-4920232-A | CHEMICAL INTERMEDIATES | BASF AKTIENGESELLSCHAFT (DE) | 1990-04-24 | — | — | US | disclosed |
| US-4804785-A | INTERMEDIATES FOR HYDROXYMETHYLOXIRANES | BASF AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| US-4723042-A | REARRANGEMENT OF AN OXYKETONE USING A PHOSPHORUS COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1988-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152257-A1 | PHENANTHROINDOLIZIDINE AND PHENANTHROQUINOLIZIDINE ALKALOID HAVING A HYDROXYL GROUP ON THE PHENANTHRENE RING THEREOF, PREPARATION METHOD AND USE THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PAH, HIPK4 | ALDH1A1 480/4885TSHR 2275/4885AKR1C1 1963/4885 |
| US-20110295019-A1 | Method for Producing Hydroxymethyl Diphenyloxiranes and Corresponding 1-azolylmethyl-1,2-diphenyloxiranes | DHPS, HMOX2, HMOX1 | ALDH1A1 11/4885TSHR 3708/4885AKR1C1 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.