Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.54 |
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CPA3 | P15088 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434110 | 0.86 | LTB4R (0.53) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL30452554 | 0.81 | TSHR (0.55) | ALDH1A1MEN1MAPTKMT2ATSHR | |
| SCHEMBL16993931 | 0.81 | TSHR (0.55) | ALDH1A1MEN1MAPTKMT2ATSHR | |
| SCHEMBL9724825 | 0.81 | TSHR (0.55) | ALDH1A1MEN1MAPTKMT2ATSHR | |
| SCHEMBL9724984 | 0.81 | LMNA (0.61) | MMEACEALDH1A1HPGDMAPK1 | |
| Benzene SCHEMBL7277187 | 0.81 | TSHR (0.58) | ALDH1A1MEN1MAPTKMT2ATSHR | |
| SCHEMBL9724964 | 0.81 | MME (0.58) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL7282286 | 0.80 | MME (0.57) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL9724871 | 0.80 | MME (0.57) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL10572943 | 0.80 | MME (0.57) | MMEACEALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |