Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16993931 | 0.83 | TSHR (0.55) | TSHRMAPTTDP1IDO1MEN1 | |
| SCHEMBL30452554 | 0.83 | TSHR (0.55) | TSHRMAPTTDP1IDO1MEN1 | |
| SCHEMBL9724867 | 0.81 | MME (0.54) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18261160 | 0.81 | IDO1 (0.58) | TSHRMAPTTDP1IDO1MEN1 | |
| SCHEMBL9724959 | 0.80 | GAA (0.55) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11580793 | 0.80 | NPC1 (0.63) | TSHRMAPTMEN1KMT2ANPC1 | |
| SCHEMBL6373420 | 0.78 | ALDH1A1 (0.76) | MEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL6373428 | 0.78 | ALDH1A1 (0.76) | MEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL6379825 | 0.78 | ALDH1A1 (0.76) | MEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL9724796 | 0.78 | HDAC1 (0.52) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |