Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.48 |
| ▸ | CTSG | P08311 | 4/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.48 |
| ▸ | CMA1 | P23946 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27678034 | 0.91 | CA2 (0.51) | LMNAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL11403740 | 0.82 | LMNA (0.50) | LMNAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL186936 | 0.82 | LMNA (0.50) | LMNAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL27796978 | 0.80 | LMNA (0.54) | LMNAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL12475390 | 0.79 | MMP2 (0.52) | PRSS1CTSGCTRB1CMA1ALDH1A1 | |
| SCHEMBL2295914 | 0.78 | ATM (0.49) | TDP1ALDH1A1CA2CYP3A4TSHR | |
| SCHEMBL28543541 | 0.78 | FOLH1 (0.47) | LMNATDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL10933511 | 0.78 | LMNA (0.50) | LMNAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL28398086 | 0.78 | ESR1 (0.56) | LMNATDP1ALDH1A1CA2CYP2D6 | |
| SCHEMBL27818296 | 0.78 | CA2 (0.50) | LMNAALDH1A1CA2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100579-A | POLYPHENYL-BASED ESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 1992-03-31 | — | — | US | disclosed |
| EP-0191600-B1 | POLYPHENYL-BASED ESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4911861-A | Mixture of at least two components | AJINOMOTO CO., INC. (JP) | 1990-03-27 | — | — | US | disclosed |
| US-4728458-A | FERROELECTRIC | AJINOMOTO CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0191600-A2 | Polyphenyl-based ester compounds and liquid crystal compositions containing same | AJINOMOTO CO., INC. (JP) | 1986-08-20 | — | — | EP | disclosed |