Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.60 |
| ▸ | NCS1 | P62166 | 1/20 | 0.54 |
| ▸ | ACP1 | P24666 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.54 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.54 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26502075 | 0.86 | CSNK1D (0.64) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL18237232 | 0.82 | CSNK1D (0.62) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL6165194 | 0.82 | CSNK1D (0.62) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL9724913 | 0.82 | CSNK1D (0.62) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| Benzene SCHEMBL7282433 | 0.81 | CSNK1D (0.64) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL4945628 | 0.76 | CSNK1D (0.60) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL386632 | 0.76 | MME (0.51) | MEN1KMT2AMAPK1MAPTMME | |
| SCHEMBL7378782 | 0.76 | MME (0.50) | MEN1KMT2AMAPK1MAPTMME | |
| SCHEMBL9724834 | 0.75 | PKM (0.61) | SMN1; SMN2ACP1MEN1NPC1RAB9A | |
| SCHEMBL13949524 | 0.75 | CSNK1D (1.00) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |