Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.50 |
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CPA3 | P15088 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346610 | 0.81 | CYP3A4 (0.41) | ACEALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7378784 | 0.78 | CPA3 (0.38) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL386632 | 0.78 | MME (0.51) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL9724924 | 0.76 | CSNK1D (0.60) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL9724834 | 0.75 | PKM (0.61) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL7271417 | 0.74 | MME (0.65) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL7346217 | 0.74 | MME (0.69) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL1914830 | 0.72 | SMN1; SMN2 (0.62) | HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL1914838 | 0.72 | SMN1; SMN2 (0.62) | HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL5097467 | 0.71 | MME (0.57) | MMEACEALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009101-A1 | MERCAPTO-AMIDE DERIVATIVES AS INHIBITORS OF THE NEUTRAL ENDOPEPTIDASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-13 | — | — | WO | disclosed |