SCHEMBL18154533

SCHEMBL18154533

CCN(CC)C(=O)Nc1ccc(OP(=S)(Oc2ccc(NC(=O)N(CC)CC)cc2)Oc2ccc(NC(=O)N(CC)CC)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.55
POLB P06746 2/20 0.55
RAB9A P51151 2/20 0.55
NPC1 O15118 1/20 0.55
TP53 P04637 1/20 0.55
HSD17B10 Q99714 2/20 0.52
ALDH1A1 P00352 3/20 0.49
MAPT P10636 2/20 0.48
MAPK1 P28482 1/20 0.47
GAA P10253 2/20 0.47
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MAOA P21397 1/20 0.45
LMNA P02545 1/20 0.44
TSHR P16473 1/20 0.44
OPRK1 P41145 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18154535 0.83 TSHR (0.54) MEN1KMT2ATSHR
SCHEMBL3302544 0.82 POLB (0.69) SMN1; SMN2POLBRAB9ANPC1TP53
SCHEMBL9724941 0.80 MAPT (0.71) SMN1; SMN2POLBRAB9ANPC1TP53
SCHEMBL11297176 0.77 KMT2A (0.67) SMN1; SMN2HSD17B10ALDH1A1MAPTMEN1
SCHEMBL12994648 0.75 POLB (0.66) SMN1; SMN2POLBRAB9ANPC1TP53
SCHEMBL13666660 0.74 RAB9A (0.59) SMN1; SMN2POLBRAB9ANPC1TP53
SCHEMBL10771088 0.74 RAB9A (0.64) SMN1; SMN2POLBRAB9ANPC1TP53
SCHEMBL8616896 0.74 POLB (0.59) SMN1; SMN2POLBRAB9ANPC1TP53
SCHEMBL9435704 0.74 GAA (0.68) SMN1; SMN2POLBRAB9ANPC1TP53
SCHEMBL6710643 0.74 POLB (0.59) SMN1; SMN2POLBRAB9ANPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428915-B Curing agent and curing accelerator (II) having flame retardant effect for curing epoxy resin 澳泽化学特罗斯特贝格有限公司 2021-02-09 CN disclosed
EP-3283495-B1 HARDENER AND CURE ACCELERANT WITH FLAME RETARDANCY EFFECT FOR CURING EPOXY RESINS (II) ALZCHEM TROSTBERG GMBH (DE) 2020-08-26 EP disclosed
EP-3283494-B1 CURING AGENT AND CURING ACCELERATOR WITH FLAME-RETARDENT EFFECT FOR CURING EPOXY RESINS ALZCHEM TROSTBERG GMBH (DE) 2019-08-07 EP disclosed
EP-3283495-A1 HARDENER AND CURE ACCELERANT WITH FLAME RETARDANCY EFFECT FOR CURING EPOXY RESINS (II) AlzChem AG (DE) 2018-02-21 EP disclosed
EP-3283494-A1 CURING AGENT AND CURING ACCELERATOR WITH FLAME-RETARDENT EFFECT FOR CURING EPOXY RESINS AlzChem AG (DE) 2018-02-21 EP disclosed
CN-107428915-A Curing agent and curing accelerator (II) having flame retardant effect for curing epoxy resin 澳泽化学股份公司 2017-12-01 CN disclosed
WO-2016166226-A1 CURING AGENT AND CURING ACCELERATOR WITH FLAME-RETARDENT EFFECT FOR CURING EPOXY RESINS ALZCHEM AG (DE) 2016-10-20 WO disclosed
WO-2016166229-A1 HARDENER AND CURE ACCELERANT WITH FLAME RETARDANCY EFFECT FOR CURING EPOXY RESINS (II) ALZCHEM AG (DE) 2016-10-20 WO disclosed