Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KLK7 | P49862 | 10/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724968 | 0.84 | KMT2A (0.65) | KLK7SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9724808 | 0.83 | MEN1 (0.53) | NPC1RAB9AKMT2ATP53ALDH1A1 | |
| SCHEMBL9724975 | 0.82 | HPGD (0.54) | HPGDKLK7KMT2AALDH1A1MEN1 | |
| SCHEMBL5037571 | 0.82 | MAPK1 (0.63) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9724829 | 0.80 | BACE1 (0.54) | SMN1; SMN2NPC1RAB9AKMT2ATP53 | |
| SCHEMBL9724978 | 0.79 | KMT2A (0.52) | KLK7SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9724923 | 0.79 | RAB9A (0.50) | SMN1; SMN2NPC1RAB9AKMT2ATP53 | |
| SCHEMBL9724950 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL9724833 | 0.76 | LMNA (0.54) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL1870609 | 0.76 | ALDH1A1 (0.62) | HPGDSMN1; SMN2KDM4ERAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |