Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724975 | 0.82 | HPGD (0.54) | KLK7ALDH1A1HPGDKMT2AMAPT | |
| Benzene SCHEMBL7286330 | 0.81 | L3MBTL1 (0.58) | KLK7ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL11770912 | 0.80 | ACE (0.61) | KLK7ALDH1A1HPGDLMNASMN1; SMN2 | |
| Benzene SCHEMBL7271414 | 0.80 | ACE (0.61) | KLK7ALDH1A1HPGDLMNASMN1; SMN2 | |
| Benzene SCHEMBL7282499 | 0.79 | MEN1 (0.50) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| Benzene SCHEMBL7310498 | 0.78 | MME (0.51) | ALDH1A1HPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL10438815 | 0.76 | HSD17B10 (0.51) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10438814 | 0.76 | HSD17B10 (0.51) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27771853 | 0.76 | ALDH1A1 (0.58) | KLK7ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL9724801 | 0.76 | HPGD (0.56) | KLK7ALDH1A1HPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115997-A2 | Derivatives of omega mercaptopropanamides, and their homologues, process for their preparation, their use as medicines, compositions containing them and intermediates obtained | ROUSSEL-UCLAF (FR) | 1984-08-15 | — | — | EP | disclosed |