Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL957709 | 0.85 | PPARA (0.41) | ALDH1A1SMN1; SMN2LMNAMAPTMCHR1 | |
| SCHEMBL1512743 | 0.80 | PGR (0.46) | MAPK1TSHRALOX15HSD17B10 | |
| SCHEMBL11704814 | 0.77 | CYP2D6 (0.41) | ALDH1A1SMN1; SMN2LMNACYP2D6MAPT | |
| SCHEMBL23816601 | 0.77 | CYP1A2 (0.42) | HTR1DALDH1A1MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL20183933 | 0.77 | ALDH1A3 (0.42) | ALDH1A1NPSR1TSHRHPGDHSD17B10 | |
| SCHEMBL28765524 | 0.77 | SRC (0.50) | ALDH1A1SMN1; SMN2LMNAMAPTCYP1A2 | |
| SCHEMBL9481170 | 0.77 | PRKCI (0.38) | ALDH1A1MAPK1LMNAMAPTTP53 | |
| SCHEMBL8646901 | 0.77 | CNR1 (0.41) | ALDH1A1GPR84 | |
| SCHEMBL356134 | 0.75 | MAPT (0.44) | ALDH1A1MAPK1SMN1; SMN2LMNAMAPT | |
| SCHEMBL3429791 | 0.75 | HSD17B3 (0.44) | LMNAMAPTESR1ESR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162305-A | Calcium lowering in blood; hypoglycemic agents, analgesics | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |