Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.67 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.67 |
| ▸ | THRA | P10827 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068476 | 0.94 | CYP4A11 (0.68) | CYP4A11CYP4F2THRATHRBLOXL2 | |
| SCHEMBL15329199 | 0.87 | CYP4A11 (0.62) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL1794550 | 0.84 | CYP4A11 (0.61) | CYP4A11CYP4F2THRATHRBLOXL2 | |
| SCHEMBL9672002 | 0.83 | PHLPP2 (0.63) | CYP4A11CYP4F2THRATHRBSIGMAR1 | |
| SCHEMBL7749439 | 0.83 | ALDH1A1 (0.56) | CYP4A11CYP4F2THRATHRBSIGMAR1 | |
| SCHEMBL10986414 | 0.82 | CYP4A11 (0.73) | CYP4A11CYP4F2THRATHRBALDH1A1 | |
| SCHEMBL6069166 | 0.82 | CYP4A11 (0.73) | CYP4A11CYP4F2THRATHRBALDH1A1 | |
| SCHEMBL4147899 | 0.82 | SIGMAR1 (0.62) | THRATHRBSIGMAR1ALDH1A1KCNH2 | |
| SCHEMBL2653147 | 0.82 | CYP4A11 (0.97) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD | |
| SCHEMBL2654656 | 0.82 | CYP4A11 (0.97) | CYP4A11CYP4F2LOXL2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137920-A | METHOD OF TREATING FUNGAL INFECTIONS | HOFFMANN-LA ROCHE INC. (US) | 1992-08-11 | — | — | US | disclosed |