Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.45 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9725446 | 0.99 | MPO (0.44) | MPOHAVCR2CCR4RAB9ASMN1; SMN2 | |
| SCHEMBL9725430 | 0.89 | MPO (0.45) | MPOHAVCR2CCR4RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9725529 | 0.87 | MPO (0.44) | MPOHAVCR2CCR4RAB9ASMN1; SMN2 | |
| SCHEMBL9725370 | 0.84 | DAO (0.53) | MPOHAVCR2CCR4RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9725468 | 0.83 | DAO (0.51) | MPOHAVCR2CCR4RAB9ASMN1; SMN2 | |
| SCHEMBL9725356 | 0.82 | CCR4 (0.43) | MPOHAVCR2CCR4RAB9ASMN1; SMN2 | |
| SCHEMBL2951726 | 0.81 | RAB9A (0.48) | RAB9ASMN1; SMN2TP53MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL9725475 | 0.81 | CCR4 (0.42) | MPOHAVCR2CCR4RAB9ASMN1; SMN2 | |
| SCHEMBL9725416 | 0.81 | MPO (0.40) | MPOHAVCR2CCR4RAB9ASMN1; SMN2 | |
| SCHEMBL9725445 | 0.81 | KDM4E (0.49) | MPOCCR4LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |