SCHEMBL972536

SCHEMBL972536

Brc1ccc(-c2cn3ccccc3n2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 15/20 1.00
NPC1 O15118 14/20 1.00
KDM4E B2RXH2 9/20 1.00
POLB P06746 1/20 1.00
GFER P55789 3/20 0.69
PKM P14618 5/20 0.65
EPHX2 P34913 1/20 0.65
HDAC6 Q9UBN7 1/20 0.61
APP P05067 2/20 0.61
PAX8 Q06710 1/20 0.61
GAA P10253 2/20 0.60
MEN1 O00255 1/20 0.60
MIF P14174 1/20 0.60
KMT2A Q03164 1/20 0.60
SMN1; SMN2 Q16637 7/20 0.60
ALDH1A1 P00352 7/20 0.60
MAPK1 P28482 2/20 0.60
NFKB1 P19838 2/20 0.59
NFKB2 Q00653 2/20 0.59
RELA Q04206 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL973267 0.98 RAB9A (0.97) RAB9ANPC1KDM4EPOLBGFER
SCHEMBL13325909 0.91 RAB9A (0.83) RAB9ANPC1KDM4EPOLBGFER
SCHEMBL13325938 0.89 RAB9A (0.80) RAB9ANPC1KDM4EPOLBGFER
SCHEMBL29396057 0.87 RAB9A (0.77) RAB9ANPC1KDM4EPOLBGFER
SCHEMBL13325735 0.86 RAB9A (0.75) RAB9ANPC1KDM4EPOLBGFER
SCHEMBL29080554 0.85 RAB9A (0.74) RAB9ANPC1KDM4EPOLBGFER
SCHEMBL31154574 0.85 RAB9A (0.74) RAB9ANPC1KDM4EPOLBGFER
SCHEMBL966793 0.85 RAB9A (0.74) RAB9ANPC1KDM4EPOLBGFER
SCHEMBL970334 0.84 RAB9A (0.73) RAB9ANPC1KDM4EPOLBGFER
SCHEMBL25343703 0.84 RAB9A (0.72) RAB9ANPC1KDM4EPOLBGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250283038-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2025-09-11 US claimed
EP-4511027-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS Université Paris Cité (FR) 2025-02-26 EP claimed
WO-2023203163-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS UNIVERSITE PARIS CITE (FR) 2023-10-26 WO claimed
CN-116813618-A Amino-substituted imidazopyridine compound and synthesis method thereof 郑州泰基鸿诺医药股份有限公司 2023-09-29 CN claimed
US-20250283038-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2025-09-11 US disclosed
WO-2025082731-A1 INTRANASAL FORMULATIONS FOR TREATING OBSTRUCTIVE SLEEP APNEA MOSANNA THERAPEUTICS AG (CH) 2025-04-24 WO disclosed
EP-4511027-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS Université Paris Cité (FR) 2025-02-26 EP disclosed
EP-3487856-B1 SUBSTITUTED DIAZAHETERO-BICYCLIC COMPOUNDS AND THEIR USE BAYER AG (DE) 2025-01-22 EP disclosed
EP-4452264-A1 COMBINATION OF A TASK1/3 CHANNEL BLOCKER WITH A NOREPINEPHRINE REUPTAKE INHIBITOR FOR THE TREATMENT OF SLEEP APNEA Bayer Aktiengesellschaft (DE) 2024-10-30 EP disclosed
CN-118852157-A Preparation method and application of imidazopyridine compound 南昌大学 2024-10-29 CN disclosed
EP-3962915-B1 SELECTIVE LIGANDS OF HUMAN CONSTITUTIVE ANDROSTANE RECEPTOR USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2024-09-04 EP disclosed
US-12041847-B2 Compound for organic electric element, organic electric element using the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-07-16 US disclosed
US-20040006083-A1 Pyrazolopyrimidines as therapeutic agents ABBVIE DEUTSCHLAND GMBH & CO KG (DE) 2004-01-08 US disclosed
US-20020156081-A1 Pyrazolopyrimidines as therapeutic agents ABBOTT LABORATORIES (US) 2002-10-24 US disclosed
US-4163745-A ANTIDIABETIC, HYPOGLYCEMIC PFIZER INC. (US) 1979-08-07 US disclosed
US-4141898-A Imidazo pyridinium quaternary salts as hypoglycemic agents PFIZER INC. (US) 1979-02-27 US disclosed
US-4129567-A IMIDAZOPYRIDINES AND ISOB IDINE PFIZER INC. (US) 1978-12-12 US disclosed
US-4097598-A Quaternary salts as hypoglycemic agents PFIZER INC. (US) 1978-06-27 US disclosed
US-4093616-A PYRROLO(1,2-A)PYRAZINIUM, PYRAZOLO(1,5-A)PYRIDINIUM, 1H-IMIDAZO(2,1-A)ISOQUINOLINIUM, OR IMIDAZO(5,1-A)ISOQUINOLINIUM SALTS PFIZER INC. (US) 1978-06-06 US disclosed
US-4044015-A Imidazopyridinium compounds as hypoglycemic agents PFIZER INC. (US) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040006083-A1 Pyrazolopyrimidines as therapeutic agents DPYD, UGT1A1, ABCB1 RAB9A 524/4885NPC1 1327/4885KDM4E 4178/4885
US-12041847-B2 Compound for organic electric element, organic electric element using the same, and electronic device thereof ORAI2, OR51E2, OR10J3 RAB9A 3265/4885NPC1 3437/4885KDM4E 832/4885
US-20250283038-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS CXCL10, IL2, IFNG RAB9A 1593/4885NPC1 1775/4885KDM4E 3343/4885
US-20020156081-A1 Pyrazolopyrimidines as therapeutic agents DPYD, CYP2D6, UGT1A1 RAB9A 975/4885NPC1 991/4885KDM4E 3921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.