Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.73 |
| ▸ | NPC1 | O15118 | 11/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | GFER | P55789 | 3/20 | 0.71 |
| ▸ | PKM | P14618 | 5/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MIF | P14174 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13325909 | 0.93 | RAB9A (0.83) | RAB9ANPC1KDM4EPOLBGFER | |
| SCHEMBL13325938 | 0.91 | RAB9A (0.80) | RAB9ANPC1KDM4EPOLBGFER | |
| SCHEMBL13325735 | 0.87 | RAB9A (0.75) | RAB9ANPC1KDM4EPOLBGFER | |
| SCHEMBL31154574 | 0.87 | RAB9A (0.74) | RAB9ANPC1KDM4EPOLBGFER | |
| SCHEMBL29080554 | 0.87 | RAB9A (0.74) | RAB9ANPC1KDM4EPOLBGFER | |
| SCHEMBL966793 | 0.87 | RAB9A (0.74) | RAB9ANPC1KDM4EPOLBGFER | |
| SCHEMBL25343703 | 0.85 | RAB9A (0.72) | RAB9ANPC1KDM4EPOLBGFER | |
| SCHEMBL3304334 | 0.84 | RAB9A (0.97) | RAB9ANPC1KDM4EPOLBGFER | |
| SCHEMBL6388717 | 0.84 | RAB9A (0.71) | RAB9ANPC1KDM4EPOLBGFER | |
| SCHEMBL972536 | 0.84 | RAB9A (1.00) | RAB9ANPC1KDM4EPOLBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114892187-B | Method for electrochemically synthesizing imidazole polycyclic aromatic compounds | 南京工业大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-112538087-B | Synthesis method of imidazopyridine compound | 温州大学新材料与产业技术研究院 | 2021-10-15 | — | — | CN | disclosed |
| EP-2752415-B1 | Fluorinated ligands for targeting peripheral benzodiazepine receptors | AUSTRALIAN NUCLEAR SCIENCE & TECH ORGANISATION (AU) | 2017-10-11 | — | — | EP | disclosed |
| US-20160050895-A1 | TRANSGENIC NON-HUMAN ORGANISMS WITH NON-FUNCTIONAL TSPO GENES | THE UNIVERSITY OF SYDNEY (AU) | 2016-02-25 | — | — | US | disclosed |
| EP-2971007-A1 | TRANSGENIC NON-HUMAN ORGANISMS WITH NON-FUNCTIONAL TSPO GENES | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014138791-A1 | TRANSGENIC NON-HUMAN ORGANISMS WITH NON-FUNCTIONAL TSPO GENES | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2014-09-18 | — | — | WO | disclosed |
| EP-2752415-A1 | Fluorinated ligands for targeting peripheral benzodiazepine receptors | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 2014-07-09 | — | — | EP | disclosed |
| US-7867629-B2 | Nitrogenous heterocyclic derivative and organic electroluminescent element employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20100209345-A1 | Fluorinated Ligands for Targeting Peripheral Benzodiazepine Receptors | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION | 2010-08-19 | — | — | US | disclosed |
| US-20040204443-A1 | Method for inducing pain relief using imidazo[1,2-a]pyridine derivatives | ZAKS ARTHUR (US) | 2004-10-14 | — | — | US | disclosed |
| WO-2004066930-A2 | METHOD FOR INDUCING PAIN RELIEF USING IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | ZAKS ARTHUR (US) | 2004-08-12 | — | — | WO | disclosed |
| EP-1071684-B1 | IMIDAZO 1,2-a]PYRIDINES AS PERIPHERAL BENZODIAZEPINE RECEPTOR BINDING AGENTS | AUSTRALIAN NUCLEAR SCIENCE TEC (AU) | 2004-03-17 | — | — | EP | disclosed |
| US-6379649-B1 | USEFUL FOR DIAGNOSIS AND TREATMENT, INCLUDING RADIOTHERAPY, OF DISORDERS THAT ARE CHARACTERIZED BY AN ABNORMAL DENSITY OF PERIPHERAL BENZODIAZEPINE RECEPTORS; NERVE SYSTEM DISPORDERS | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 2002-04-30 | — | — | US | disclosed |
| EP-1071684-A4 | IMIDAZO 1,2-a]PYRIDINES AS PERIPHERAL BENZODIAZEPINE RECEPTOR BINDING AGENTS | AUSTRALIAN NUCLEAR SCIENCE TEC (AU) | 2001-10-04 | — | — | EP | disclosed |
| EP-1071684-A1 | IMIDAZO 1,2-a]PYRIDINES AS PERIPHERAL BENZODIAZEPINE RECEPTOR BINDING AGENTS | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999051594-A1 | IMIDAZO[1,2-a]PYRIDINES AS PERIPHERAL BENZODIAZEPINE RECEPTOR BINDING AGENTS | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 1999-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100209345-A1 | Fluorinated Ligands for Targeting Peripheral Benzodiazepine Receptors | GABRA6, GABRA1, GABRA2 | RAB9A 1716/4885NPC1 524/4885KDM4E 3090/4885 |
| US-20040204443-A1 | Method for inducing pain relief using imidazo[1,2-a]pyridine derivatives | P2RY1, ITPR1, P2RX3 | RAB9A 1094/4885NPC1 939/4885KDM4E 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.