SCHEMBL9725443

SCHEMBL9725443

CC(Cn1c(=O)[nH]c2ccc(Cl)cc21)N(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.52
B3GNT2 Q9NY97 1/20 0.49
PGR P06401 5/20 0.48
CBX7 O95931 1/20 0.46
CDYL2 Q8N8U2 1/20 0.46
CDYL Q9Y232 1/20 0.46
CDY1; CDY1B Q9Y6F8 1/20 0.46
PSMB8 P28062 1/20 0.42
MAOB P27338 1/20 0.42
LMNA P02545 2/20 0.42
HTT P42858 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9725465 0.99 DAO (0.51) DAOB3GNT2PGRCBX7CDYL2
SCHEMBL6910220 0.78 PGR (0.72) DAOPGRCBX7CDYL2CDYL
SCHEMBL9725376 0.78 DAO (0.51) DAOPGRCBX7CDYL2CDYL
Hydrochloric Acid SCHEMBL9725385 0.77 MPO (0.50) DAOPGRCBX7CDYL2CDYL
SCHEMBL10248043 0.76 PGR (0.51) DAOB3GNT2PGRCBX7CDYL2
SCHEMBL11708301 0.74 DAO (0.57) DAOPGRCBX7CDYL2CDYL
SCHEMBL10284498 0.73 PGR (0.64) DAOPGRCBX7CDYL2CDYL
SCHEMBL318631 0.73 DAO (0.55) DAOPGRCBX7CDYL2CDYL
SCHEMBL11703773 0.73 DAO (0.59) DAOB3GNT2PGRCBX7CDYL2
SCHEMBL2968866 0.72 PGR (0.72) DAOB3GNT2PGRPSMB8MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5162318-A Which have pulmonary surfactant secretion promoting activity YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1992-11-10 US disclosed
EP-0454330-A1 Benzimidazolinone derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1991-10-30 EP disclosed