Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9725464 | 0.99 | MAOB (0.46) | MAOBPOLBMPOLTA4HCCR4 | |
| SCHEMBL9725490 | 0.85 | HTR2A (0.49) | MAOBCCR4KDM4EALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9725431 | 0.84 | HTR2A (0.48) | MAOBCCR4RAB9AKDM4EALDH1A1 | |
| SCHEMBL28967652 | 0.79 | MAOB (0.62) | MAOBPOLBKMT2ABRD4GRIA2 | |
| SCHEMBL4419395 | 0.79 | MEN1 (0.63) | POLBMPORAB9AHAVCR2ALDH1A1 | |
| SCHEMBL9725403 | 0.78 | DAO (0.53) | MPOCCR4RAB9AHAVCR2DAO | |
| Hydrochloric Acid SCHEMBL9725349 | 0.77 | RAB9A (0.64) | POLBMPORAB9AHAVCR2ALDH1A1 | |
| SCHEMBL9725419 | 0.77 | SIGMAR1 (0.58) | POLBMPORAB9AHAVCR2ALDH1A1 | |
| SCHEMBL9725422 | 0.77 | DAO (0.51) | MAOBMPOCCR4RAB9AHAVCR2 | |
| SCHEMBL9725430 | 0.77 | MPO (0.45) | MPOCCR4RAB9AHAVCR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |