Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CBX7 | O95931 | 1/20 | 0.40 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.40 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.40 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9725467 | 0.99 | SIGMAR1 (0.57) | SIGMAR1B3GNT2ALDH1A1GLASMN1; SMN2 | |
| SCHEMBL4419395 | 0.78 | MEN1 (0.63) | ALDH1A1SMN1; SMN2CYP1A2POLBMPO | |
| SCHEMBL9725449 | 0.77 | MAOB (0.47) | ALDH1A1SMN1; SMN2CYP1A2POLBMPO | |
| SCHEMBL9725403 | 0.77 | DAO (0.53) | B3GNT2CYP1A2MPORAB9AHAVCR2 | |
| Hydrochloric Acid SCHEMBL9725349 | 0.76 | RAB9A (0.64) | ALDH1A1SMN1; SMN2CYP1A2POLBMPO | |
| Hydrochloric Acid SCHEMBL9725464 | 0.76 | MAOB (0.46) | ALDH1A1SMN1; SMN2CYP1A2POLBMPO | |
| SCHEMBL9725430 | 0.76 | MPO (0.45) | B3GNT2SMN1; SMN2CYP1A2MPORAB9A | |
| SCHEMBL9725422 | 0.76 | DAO (0.51) | MPORAB9AHAVCR2 | |
| Hydrochloric Acid SCHEMBL9725357 | 0.76 | DAO (0.51) | B3GNT2CYP1A2MPORAB9AHAVCR2 | |
| SCHEMBL9725376 | 0.76 | DAO (0.51) | ALDH1A1SMN1; SMN2CYP1A2MPOCBX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |