Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 9/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232162 | 0.87 | VNN1 (0.52) | VNN1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL12004538 | 0.85 | GAA (0.54) | VNN1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL11890771 | 0.85 | HDAC1 (0.53) | VNN1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL12061580 | 0.83 | HDAC1 (0.51) | VNN1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL9725390 | 0.82 | MAPT (0.56) | VNN1NPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL11754772 | 0.80 | KDM4E (0.49) | VNN1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL15687652 | 0.80 | CA1 (0.61) | HDAC1ALDH1A1HIF1AKDM4E | |
| SCHEMBL12044040 | 0.78 | ALDH1A1 (0.69) | VNN1MEN1ALDH1A1KMT2ARAB9A | |
| Bicarbonate SCHEMBL8979728 | 0.78 | HDAC1 (0.62) | HDAC1HDAC3HDAC2NCOR2NCF1 | |
| SCHEMBL23619201 | 0.77 | PTGER4 (0.49) | HDAC1HDAC3HDAC2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| CN-1060837-A | BENZIMIDAZOLINONE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 1992-05-06 | — | — | CN | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |