Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993941 | 0.88 | GAA (0.65) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL30535169 | 0.88 | GAA (0.65) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL9725455 | 0.87 | VNN1 (0.57) | VNN1ALDH1A1KDM4EHDAC1HDAC3 | |
| SCHEMBL11789175 | 0.83 | CFD (0.51) | ALDH1A1KDM4EGAAHDAC1HDAC8 | |
| SCHEMBL15687652 | 0.83 | CA1 (0.61) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL11232662 | 0.79 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL11741197 | 0.79 | HDAC8 (0.50) | VNN1HDAC1HDAC8HDAC6 | |
| SCHEMBL9256123 | 0.79 | HDAC8 (0.47) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL11267256 | 0.78 | PRKCI (0.65) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL29117538 | 0.78 | KMT2A (0.59) | GAAMAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310537-A | ANTHELMINTICS AND FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| US-4060636-A | Acetyl- and carbalkoxythioureidobenzophenones as anthelmintic agents | ROHM AND HAAS COMPANY (US) | 1977-11-29 | — | — | US | disclosed |