Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9725400 | 0.99 | LMNA (0.55) | TMEM97LMNAGRIN1GRIN2BDAO | |
| SCHEMBL9725368 | 0.99 | TMEM97 (0.57) | TMEM97LMNAGRIN1GRIN2BDAO | |
| Hydrochloric Acid SCHEMBL9725484 | 0.97 | LMNA (0.57) | TMEM97LMNAGRIN1GRIN2BDAO | |
| SCHEMBL738090 | 0.89 | HTR7 (0.50) | TMEM97LMNAGRIN1GRIN2BDAO | |
| Hydrochloric Acid SCHEMBL9725415 | 0.88 | HTR7 (0.49) | TMEM97LMNADAOHTR7HTR1A | |
| SCHEMBL11199049 | 0.81 | P2RX7 (0.76) | LMNAHTR7HTR1AMEN1SLC22A2 | |
| SCHEMBL11708301 | 0.81 | DAO (0.57) | LMNADAOHTR7HTR1AMEN1 | |
| SCHEMBL4042957 | 0.80 | LMNA (0.79) | LMNAHTR7HTR1AMEN1NR1I2 | |
| SCHEMBL11703773 | 0.80 | DAO (0.59) | LMNADAOHTR7MEN1CYP1A2 | |
| SCHEMBL318631 | 0.80 | DAO (0.55) | LMNADAOHTR7HTR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | claimed |
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |