SCHEMBL972550

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL972757	0.90	SMPD3 (0.41)	SMPD3BTK
	SCHEMBL974290	0.89	BTK (0.38)	SMPD3BTK
	SCHEMBL973618	0.89	PCSK9 (0.43)	SMPD3KMT2AEPHX2SYKPCSK9
	SCHEMBL973992	0.88	BTK (0.45)	SMPD3BTK
	SCHEMBL973987	0.87	SMPD3 (0.43)	SMPD3TRPV1KMT2ATRPM8USP30
	SCHEMBL974125	0.86	CRHR1 (0.43)	SMPD3KMT2ASYKPCSK9BTK
	SCHEMBL973973	0.86	NAAA (0.46)	SMPD3KMT2A
	SCHEMBL973310	0.85	TRPV1 (0.41)	SMPD3TRPV1KMT2ATRPM8USP30
	SCHEMBL973959	0.84	BTK (0.38)	SMPD3BTK
	SCHEMBL973350	0.84	SMPD3 (0.38)	SMPD3TRPV1TRPM8USP30MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.