SCHEMBL972757

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL974290	0.92	BTK (0.38)	SMPD3BTKACKR3PPARDPPARA
	SCHEMBL973992	0.90	BTK (0.45)	SMPD3BTKGLSPPARDPPARA
	SCHEMBL972550	0.90	SMPD3 (0.43)	SMPD3BTK
	SCHEMBL973959	0.89	BTK (0.38)	SMPD3BTKMAPK1
	SCHEMBL973973	0.89	NAAA (0.46)	SMPD3GLSPPARDPPARACCNE1
	SCHEMBL972307	0.87	SMPD3 (0.39)	SMPD3BTKACKR3PPARDPPARA
	SCHEMBL973612	0.86	SMPD3 (0.41)	SMPD3BTKGLSACKR3MAPK1
	SCHEMBL972939	0.85	BTK (0.38)	SMPD3BTKGLSPPARDPPARA
	SCHEMBL974402	0.85	BTK (0.37)	SMPD3BTKCCNE1CDK2GRM5
	SCHEMBL974669	0.84	HRH3 (0.39)	SMPD3BTKGLSACKR3MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.