Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725757 | 1.00 | ALOX5 (0.40) | ALOX5KMT2APOLBPKMPTPN1 | |
| SCHEMBL14944873 | 0.79 | KDM4E (0.48) | ALOX5KMT2APOLBPKMPTPN1 | |
| SCHEMBL8321455 | 0.77 | KMT2A (0.44) | ALOX5KMT2APOLBPKMPTPN1 | |
| SCHEMBL27728696 | 0.76 | KMT2A (0.50) | ALOX5KMT2APOLBPKMPTPN1 | |
| SCHEMBL11151822 | 0.76 | KMT2A (0.58) | ALOX5KMT2APOLBPKMPTPN1 | |
| SCHEMBL15272598 | 0.76 | KMT2A (0.58) | ALOX5KMT2APOLBPKMPTPN1 | |
| SCHEMBL15272327 | 0.76 | KMT2A (0.58) | ALOX5KMT2APOLBPKMPTPN1 | |
| SCHEMBL10147174 | 0.74 | KMT2A (0.48) | ALOX5KMT2APOLBPKMPTPN1 | |
| SCHEMBL28961573 | 0.74 | ALOX5 (0.42) | ALOX5KMT2APOLBPKMPTPN1 | |
| SCHEMBL7319840 | 0.74 | MIF (0.51) | KMT2APOLBPKMPTPN1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |