Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | CTSL | P07711 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725804 | 0.81 | CTSL (0.42) | CTSKCTSLCTSBCTSSPTPRB | |
| SCHEMBL7268135 | 0.72 | REN (0.49) | — | |
| SCHEMBL7269394 | 0.72 | REN (0.49) | — | |
| SCHEMBL9725802 | 0.72 | REN (0.49) | — | |
| SCHEMBL9725773 | 0.70 | REN (0.46) | CTSKCTSLCTSBCTSS | |
| SCHEMBL9725771 | 0.70 | REN (0.47) | CTSKCTSLCTSBCTSS | |
| SCHEMBL9725765 | 0.69 | CTSL (0.47) | CTSKCTSLCTSBCTSSPTPRB | |
| SCHEMBL9725827 | 0.69 | REN (0.45) | CTSKCTSLCTSBCTSS | |
| SCHEMBL3338146 | 0.69 | ATM (0.58) | CTSKCTSLCTSSCYP3A4TSHR | |
| SCHEMBL27674564 | 0.69 | ATM (0.58) | CTSKCTSLCTSSCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | disclosed |