Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 2/20 | 0.39 |
| ▸ | AHCY | P23526 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725898 | 0.86 | OPRD1 (0.39) | GRM7AHCYOPRD1 | |
| Hydrochloric Acid SCHEMBL7634870 | 0.85 | OPRD1 (0.38) | GRM7AHCYOPRD1 | |
| Hydrochloric Acid SCHEMBL7634867 | 0.85 | OPRD1 (0.38) | GRM7AHCYOPRD1 | |
| SCHEMBL9726022 | 0.78 | HTR1A (0.44) | NPY5R | |
| SCHEMBL27280948 | 0.76 | AHCY (0.36) | GRM7AHCY | |
| SCHEMBL27280950 | 0.76 | AHCY (0.36) | GRM7AHCY | |
| SCHEMBL10416255 | 0.75 | ELANE (0.35) | AHCYDRD3OPRD1NPY5R | |
| Oxalic Acid SCHEMBL7369077 | 0.75 | ELANE (0.36) | GRM7AHCYOPRD1NPY5R | |
| Acetic Acid SCHEMBL10568456 | 0.75 | ELANE (0.36) | GRM7AHCYDRD3OPRD1NPY5R | |
| Hydrochloric Acid SCHEMBL9726065 | 0.72 | ACE (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098892-A | Angiotensin converting enzyme inhibitors as hypotensive agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| US-4822818-A | ANTIHYPERTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4474692-A | L-Alanyl-N-(indan-2-yl)glycine, its esters and salts thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-10-02 | — | — | US | disclosed |
| EP-0051391-B1 | BICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-09-05 | — | — | EP | disclosed |
| EP-0051391-A1 | Bicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-05-12 | — | — | EP | disclosed |