Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624712 | 0.78 | ALDH1A1 (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL23845723 | 0.71 | NR4A1 (0.38) | ALDH1A1 | |
| SCHEMBL8463515 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL9726069 | 0.69 | F13A1 (0.33) | — | |
| SCHEMBL12410908 | 0.68 | FPR2 (0.33) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9726092 | 0.66 | LMNA (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9805593 | 0.66 | ALDH1A1 (0.61) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL16136347 | 0.66 | FPR2 (0.49) | SMN1; SMN2MAPTKMT2AL3MBTL1GAA | |
| SCHEMBL1431164 | 0.65 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL15357759 | 0.65 | SMN1; SMN2 (0.34) | RAB9ASMN1; SMN2MAPTALPGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098707-A | Thioimidazolium salts as anticoagulants for platelet aggregation inhibitors | MERCK & CO., INC. (US) | 1992-03-24 | — | — | US | disclosed |