Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | PPARG | P37231 | 7/20 | 0.33 |
| ▸ | PPARD | Q03181 | 7/20 | 0.33 |
| ▸ | PPARA | Q07869 | 7/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265251 | 0.86 | FFAR3 (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL24331732 | 0.79 | FFAR3 (0.42) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6138052 | 0.78 | LMNA (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7332844 | 0.76 | TDP1 (0.32) | TSHRTDP1ALOX15HSD17B10LMNA | |
| SCHEMBL28613948 | 0.73 | MMP1 (0.47) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10950026 | 0.72 | AKR1B1 (0.56) | TSHRAKR1B1GPR84PPARGPPARD | |
| SCHEMBL14435161 | 0.71 | GPR84 (0.58) | TSHRAKR1B1GPR84PPARGPPARD | |
| SCHEMBL1115961 | 0.71 | GPR84 (0.58) | TSHRAKR1B1GPR84PPARGPPARD | |
| SCHEMBL11715824 | 0.70 | FFAR3 (0.46) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Ammonia Solution, Strong SCHEMBL11417642 | 0.69 | GPR84 (0.56) | TSHRAKR1B1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122514-A | Administering renin inhibitor | ABBOTT LABORATORIES (US) | 1992-06-16 | — | — | US | disclosed |