Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 8/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726244 | 0.74 | HTR7 (0.50) | HTR1APARP1 | |
| SCHEMBL9726234 | 0.73 | HTR7 (0.49) | PARP1 | |
| SCHEMBL14601668 | 0.69 | SIGMAR1 (0.60) | HTR1A | |
| SCHEMBL354297 | 0.69 | SIGMAR1 (0.58) | HTR1APARP1 | |
| SCHEMBL9093176 | 0.68 | GAA (0.53) | HTR1ADRD4PARP1GAAHTT | |
| SCHEMBL256663 | 0.68 | SIGMAR1 (0.63) | HTR1APARP1 | |
| SCHEMBL6795806 | 0.67 | PARP1 (0.78) | PARP1 | |
| SCHEMBL9867159 | 0.67 | SIGMAR1 (0.60) | HTR1ADRD4 | |
| SCHEMBL5541146 | 0.67 | SIGMAR1 (0.60) | HTR1A | |
| SCHEMBL9726237 | 0.67 | SIGMAR1 (0.60) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130313-A | Central nervous system disorders, cardiovascular disorders or gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1992-07-14 | — | — | US | disclosed |