Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726208 | 0.74 | HTR1A (0.48) | HTR1APARP1 | |
| SCHEMBL5757859 | 0.74 | GAA (0.62) | HTR7HTR1AALDH1A1 | |
| SCHEMBL354297 | 0.74 | SIGMAR1 (0.58) | SIGMAR1HTR1APARP1 | |
| SCHEMBL5755950 | 0.72 | CCR3 (0.54) | HTR7SIGMAR1 | |
| SCHEMBL11175889 | 0.71 | PARP1 (0.55) | HTR7SIGMAR1HTR1APARP1 | |
| SCHEMBL9726233 | 0.71 | SIGMAR1 (0.61) | SIGMAR1HTR1A | |
| SCHEMBL9867159 | 0.71 | SIGMAR1 (0.60) | SIGMAR1HTR1A | |
| SCHEMBL5541146 | 0.71 | SIGMAR1 (0.60) | SIGMAR1HTR1A | |
| SCHEMBL14601668 | 0.71 | SIGMAR1 (0.60) | SIGMAR1HTR1A | |
| SCHEMBL9726237 | 0.71 | SIGMAR1 (0.60) | SIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130313-A | Central nervous system disorders, cardiovascular disorders or gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1992-07-14 | — | — | US | disclosed |