Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 5/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667623 | 0.87 | HTR2A (0.60) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9757250 | 0.85 | HTR7 (0.66) | HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL6995331 | 0.82 | HTR2A (0.56) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6991299 | 0.80 | HTR2A (0.53) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6991294 | 0.80 | HTR2A (0.53) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9726227 | 0.79 | DRD2 (0.72) | HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL9757356 | 0.79 | HTR2A (0.57) | HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL6995673 | 0.76 | HTR2A (0.58) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11799453 | 0.75 | HTR2A (0.62) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7816022 | 0.75 | HTR2C (0.56) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130313-A | Central nervous system disorders, cardiovascular disorders or gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1992-07-14 | — | — | US | disclosed |